Arsenal have been installed as the favourites in the Premier League outright winner market.
Rodri's injury, coupled with Manchester City dropping points away to Newcastle United in their first game without the influential midfielder, has seen Arsenal move to the top of the PL odds. Despite Liverpool leading the way after seven games, they are third favourites in the betting.
News that Rodri is set for a long spell on the sidelines due to requiring surgery on a knee injury has badly hurt City's chances of winning the Premier League title for the fifth year in a row.
Pep Guardiola has suggested that the Spain star cannot be replaced in the January transfer window, but City may need to think again after they succumbed to a second straight draw.
City are now at around 2/1 in the Premier League winner betting odds, with Arsenal offered at 5/4. The Gunners needed two late goals to down Leicester City at the Emirates on Sunday but, even though they are third in the league, they are now title favourites in the eyes of the bookies.
Liverpool won 2-1 away to Wolves in matchday six, with Arne Slot's impressive side now sitting right at the top of the Premier League after Mo Salah's penalty clinched their victory at Molineux. But the Reds can still be backed at 5/1 to win the Premier League title, behind Arsenal and City.
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Cole Palmer's sensational display in Chelsea's home win against Brighton leaves the Blues fourth in the table as they continue to make strides under new boss Enzo Maresca.
Chelsea are available at around 4/5 in the top-four finish Premier League betting odds after collecting a third straight league win. There are no doubts about Chelsea's attacking potency with their 15 goals scored so far more than anyone else in the Premier League after six rounds.
Their main rivals for the fourth Champions League qualification spot look to be Tottenham, who shone in a 3-0 win away to Manchester United. Spurs' summer signing Dominic Solanke found the net and Brennan Johnson continued his hot streak by scoring for the fourth game in a row.
Spurs are eighth in the table but are being offered at 11/4 in the Premier League top-four odds.
Aston Villa could only draw 2-2 away to Ipswich Town at the weekend and Unai Emery's side are now priced at 9/2 to be in the top four at the end of the season. Newcastle holding champions City at home means their top-four odds have shifted to 5/1 but an injury to star striker Alexander Isak could hobble them in the short term.
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The race for the Golden Boot looked to be one-sided going into the weekend with City striker Erling Haaland well clear of the competition, but Palmer is shaping up as his main competition.
Chelsea's star man moved to six goals for the season and although he is still four behind the Norway international, Palmer's PL top goalscorer betting odds have now been cut to just 12/1.
Haaland is the runaway favourite at a price of 1/8 with the bookmakers but an injury to the City striker could open the door for the chasing pack to catch him, so the market is worth watching.
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United's 3-0 defeat at home to Tottenham saw their performance lambasted as "disgraceful" by Gary Neville, increasing the growing pressure on beleaguered boss Erik ten Hag. Having limped to an eighth-place finish in the Premier League last term, United are sitting in the bottom half of the table after six games and they are priced just 7/4 to finish in the top six of the league table.
A run of three games without a win has seen the vultures begin to circle above Ten Hag's head. He is now seen as the favourite in the next manager to leave their Premier League job betting market, with the bookmakers offering a price of 17/20 for the Dutchman to be shown the door, a big change from the recent 8/1 odds that were being offered on Ten Hag being the first sacking.
Sean Dyche had previously headed that market but the Englishman boosted his position with Everton's crucial 2-1 victory at home to Crystal Palace at the weekend, secured from 1-0 down thanks to a fine brace scored by winger Dwight McNeil. Dyche has now drifted out to 9/1 to be sacked next - despite Everton's takeover - behind Ten Hag and Wolves boss Gary O'Neil (6/1).
In terms of Ten Hag's replacement, Ruud Van Nistelrooy is currently the bookies favourite to be the next permanent Manchester United manager at 2/1, with Southgate close behind at 3/1.
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Wolves are marooned at the bottom of the Premier League table following their latest loss to Liverpool at the weekend, with O'Neil's men only able to collect a single league point to date. But the fixtures have not exactly been kind to the Wolves, and we expect them to be safe as soon as they move into more favourite matchups.
Despite being bottom, Wolves can still be backed at 2/1 to be relegated this season. The 16 goals they have conceded means they have the league's worst defence and must tighten up.
The promoted trio of Southampton, Ipswich Town and Leicester City are all priced up at lower odds with none of them yet being able to taste victory in the Premier League this season. Southampton's struggles continued on Monday with a 3-1 loss to Bournemouth. The Saints were 3-0 down at the break and are now 2/7 favourites to be relegated, with Ipswich 11/10,
Leicester, meanwhile, showed signs of life at Arsenal but were downed by late goals, but there are positives to take from the fact they have found the net in every league game this season. The Foxes are at a top price of around 8/13 in the Premier League relegation betting odds, while Everton's win pushed them to 9/4. Forest, Crystal Palace and Brentford are all at 8/1.
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Steven is an experienced iGaming content writer who has been working in the industry since 2018. He is passionate about sports betting and enjoys writing about all aspects of the industry, including bookmaker reviews, betting tips and strategies, and news and analysis.